Michael T. Marty, PhD
Assistant Professor at University of Arizona
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Dr. Marty completed his PhD training as a Springborn Fellow under the guidance of Stephan Sligar at UIUC. In 2013, he began his postdoctoral research with Carol Robinson at the University of Oxford. There, he developed UniDec software for deconvolution of mass and ion mobility spectra. Applying UniDec with high-resolution Orbitrap mass spectrometry, he discovered that membrane proteins ejected from Nanodiscs retained a full annular belt of bound lipids. He joined the Department of Chemistry and Biochemistry at the University of Arizona in 2016. The Marty lab focuses on the characterization of membrane proteins and antimicrobial peptides by mass spectrometry. His lab works at the interface of chemistry and biochemistry, combining cutting-edge analytical methodologies with biotechnology.
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Education
- B.A. 2010, St. Olaf College
- Ph.D. 2013, University of Illinois at Urbana-Champaign
- Postdoctoral Researcher 2013-2016, University of Oxford
Awards and Honors
- NSF CAREER Award, 2019
- NIH Maximizing Invesitagor's Research Award (MIRA), 2019
- American Society for Mass Spectrometry Research Award, 2018
- Bisgrove Scholar Award, 2017
- Robert C. and Carolyn J. Springborn Fellow, 2010-2013
- Phi Beta Kappa, 2009
Notable Publications
- Zhang, G.; Keener, J.E.; Marty, M.T. “Measuring Remodeling of the Lipid Environment Surrounding Membrane Proteins with Lipid Exchange and Native Mass Spectrometry.” Anal. Chem. 2020, DOI: 10.1021/acs.analchem.1020c00786.
- Townsend, J.A.; Keener, J.E.; Miller, Z.; Prell, J.S.; Marty, M.T. "Imidazole Derivatives Improve Charge Reduction and Stabilization for Native Mass Spectrometry." Anal. Chem. 2019, DOI: 10.1021/acs.analchem.1029b04263.
- Keener, J.E.; Zambrano, D.E.; Zhang, G.; Zak, C.K.; Reid, D.J.; Deodhar, B.S.; Pemberton, J.E.; Prell, J.S.; Marty, M.T. Chemical additives enable native mass spectrometry measurement of membrane protein oligomeric state within intact nanodiscs. J. Am. Chem. Soc. 2019, 141, 1054-1061.
