Dr. Elizabeth Neumann
Career summary
The Neumann lab joined the Chemistry Department at UC Davis in the summer of 2022 and focuses on understanding the molecular and cellular architecture behind neurological diseases. The research is highly interdisciplinary and involves developing analytical tools and multimodal imaging methods for understanding complex biological phenomena. In sum, we use matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) to measure hundreds to thousands of molecular features within a biological sample without disturbing their spatial content. We can then couple this chemically informative information to other powerful technologies, such as highly multiplexed immunofluorescence , spectroscopy, or transcriptomics, to get a more complete picture of complex biological systems. We are always looking for enthusiastic and passionate students to join as well as collaborators in any field for collaboration, as these approaches are applicable to most biological systems.
Awards and Professional Highlights
Vanderbilt University, Nashville, TN
University of Illinois at Urbana-Champaign, Urbana, IL
Baylor University, Waco, TX
- ASMS Asilomar 2019 Travel Award
- Dr. Laura Busenlehner Award for outstanding postdoctoral trainee for discovery science
- NIH Toxicology T32
- NIH NIDDK F32
University of Illinois at Urbana-Champaign, Urbana, IL
- 2019 ACS Partners for Progress and Prosperity Award
- 2019 Graduate Student Leadership Award
- National Science Foundation-Graduate Research Fellowship
- Springborn Endowment Fellowship
- Illinois Distinguished Fellowship
Baylor University, Waco, TX
- President’s Gold Scholarship
- Alfred David Denton, Jr., Memorial Endowed Scholarship
- C. Clifton and Betsy Robinson Scholarship
- Nancy Tiner Chemistry Scholarship
- ACS Outstanding Senior Undergraduate Chemistry Student Award
Education
- NIH Postdoctoral Fellow at Vanderbilt University under the supervision of Richard Caprioli and Jeffrey Spraggins
- NSF Doctoral Fellow at University of Illinois at Urbana-Champaign under the supervision of Jonathan Sweedler
- BS in Chemistry from Baylor University with research performed under the supervision of Touradj Solouki
publications
Gorman, Brittney L., Catelynn C. Shafer, Nagarjunachary Ragi, Kumar Sharma, Elizabeth K. Neumann, and Christopher R. Anderton. "Imaging and spatially resolved mass spectrometry applications in nephrology." Nature Reviews Nephrology (2025): 1-18.
Stevens, Nathanial C., Tong Shen, Joshua Martinez, Veneese JB Evans, Morgan C. Domanico, Elizabeth K. Neumann, Laura S. Van Winkle, and Oliver Fiehn. "Resolving multi-image spatial lipidomic responses to inhaled toxicants by machine learning." Nature Communications 16, no. 1 (2025): 2954.
Shafer, Catelynn C., and Elizabeth K. Neumann. "Optimized combination of MALDI MSI and immunofluorescence for neuroimaging of lipids within cellular microenvironments." Frontiers in Chemistry 12 (2024): 1334209.
Shafer, Catelynn C., Jacopo Di Lucente, Ulises Ruiz Mendiola, Izumi Maezawa, Lee-Way Jin, and Elizabeth K. Neumann. "Effects of sex and western diet on spatial lipidomic profiles for the hippocampus, cortex, and corpus callosum in mice using MALDI MSI." Journal of the American Society for Mass Spectrometry 35, no. 11 (2024): 2554-2563.
Bender, Kayle J., Yongheng Wang, Chuo Ying Zhai, Zoe Saenz, Aijun Wang, and Elizabeth K. Neumann. "Sample preparation method for MALDI mass spectrometry imaging of fresh-frozen spines." Analytical Chemistry 95, no. 47 (2023): 17337-17346.
Stevens, Nathanial C., Tong Shen, Joshua Martinez, Veneese JB Evans, Morgan C. Domanico, Elizabeth K. Neumann, Laura S. Van Winkle, and Oliver Fiehn. "Resolving multi-image spatial lipidomic responses to inhaled toxicants by machine learning." Nature Communications 16, no. 1 (2025): 2954.
Shafer, Catelynn C., and Elizabeth K. Neumann. "Optimized combination of MALDI MSI and immunofluorescence for neuroimaging of lipids within cellular microenvironments." Frontiers in Chemistry 12 (2024): 1334209.
Shafer, Catelynn C., Jacopo Di Lucente, Ulises Ruiz Mendiola, Izumi Maezawa, Lee-Way Jin, and Elizabeth K. Neumann. "Effects of sex and western diet on spatial lipidomic profiles for the hippocampus, cortex, and corpus callosum in mice using MALDI MSI." Journal of the American Society for Mass Spectrometry 35, no. 11 (2024): 2554-2563.
Bender, Kayle J., Yongheng Wang, Chuo Ying Zhai, Zoe Saenz, Aijun Wang, and Elizabeth K. Neumann. "Sample preparation method for MALDI mass spectrometry imaging of fresh-frozen spines." Analytical Chemistry 95, no. 47 (2023): 17337-17346.
upcoming
Neumann, E. K., Patterson, N. H., Tideman, L., Sharman, K., Migas, L., Allen, J. L., Yang, H., Anderson, D. M., Gutierrez, D., Brewer, M., deCaestecker, M. P., Harris, R., Fogo, A., Van de Plas, R., Caprioli, R. M., Spraggins, J. M. “Molecular classification and profiles of functional regions within Eleven Human Kidneys”, under review, Nature.
Sharman, K., Patterson, N. H., Neumann, E. K., Weiss, A., Gutierrez, D. B., Van de Plas, R., Skaar, E. P., Caprioli, R. M., Spraggins, J. M. “Analyzing High-Dimensional Spatially Targeted Proteomics Data During Staphylococcus aureus Infection”, under revision.
Sharman, K., Patterson, N. H., Neumann, E. K., Weiss, A., Gutierrez, D. B., Van de Plas, R., Skaar, E. P., Caprioli, R. M., Spraggins, J. M. “Analyzing High-Dimensional Spatially Targeted Proteomics Data During Staphylococcus aureus Infection”, under revision.
Professional Membership
ASMS American Society for Mass Spectrometry
ACS American Chemistry Society
ASMS American Society for Mass Spectrometry
ACS American Chemistry Society
